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1

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study

John R Teerlink, Marco Metra, G Michael Felker, Piotr Ponikowski, Adriaan A Voors, Beth Davison Weatherley, Alon Marmor, Amos Katz, Jacek Grzybowski, Elaine Unemori, Sam L Teichman, Gad Cotter

Journal:

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

2

Lack of aspirin effect: aspirin resistance or resistance to taking aspirin?

Gad Cotter, Eyal Shemesh, Miriam Zehavi, Irit Dinur, Abraham Rudnick, Olga Milo, Zvi Vered, Rikardo Krakover, Edo Kaluski, Abraham Kornberg

Journal:

American Heart Journal

Year:

2004

Language:

english

File:

PDF, 151 KB

english, 2004

3

Support ventilation versus conventional oxygen

Gad Cotter, Zvi Vered, Isaac Shpirer

Journal:

Year:

2001

Language:

english

File:

PDF, 53 KB

english, 2001

4

Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema

Gad Cotter, Einat Metzkor, Edo Kaluski, Zwi Faigenberg, Rami Miller, Avi Simovitz, Ori Shaham, Doron Marghitay, Maya Koren, Alex Blatt, Yaron Moshkovitz, Ronit Zaidenstein, Ahuva Golik

Journal:

Year:

1998

Language:

english

File:

PDF, 74 KB

english, 1998

5

The burden of heart failure in Africa

Cotter, Gad, Cotter-Davison, Beth, Ogah, Okechukwu S.

Journal:

European Journal of Heart Failure

Year:

2013

Language:

english

File:

PDF, 125 KB

english, 2013

6

Recent developments in cardiac output determination by bioimpedance: comparison with invasive cardiac output and potential cardiovascular applications

Moshkovitz, Yaron, Kaluski, Edo, Milo, Olga, Vered, Zvi, Cotter, Gad

Journal:

Current Opinion in Cardiology

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004

7

Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial design

Bartunek, Jozef, Davison, Beth, Sherman, Warren, Povsic, Thomas, Henry, Timothy D., Gersh, Bernard, Metra, Marco, Filippatos, Gerasimos, Hajjar, Roger, Behfar, Atta, Homsy, Christian, Cotter, Gad, Wij

Journal:

European Journal of Heart Failure

Year:

2016

Language:

english

File:

PDF, 368 KB

english, 2016

8

Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure

Demissei, Biniyam G., Postmus, Douwe, Cleland, John G., O'Connor, Christopher M., Metra, Marco, Ponikowski, Piotr, Teerlink, John R., Cotter, Gad, Davison, Beth A., Givertz, Michael M., Bloomfield, Da

Journal:

European Journal of Heart Failure

Year:

2017

Language:

english

File:

PDF, 218 KB

english, 2017

9

Serial assessment of spot urine sodium predicts effectiveness of decongestion and outcome in patients with acute heart failure

Biegus, Jan, Zymliński, Robert, Sokolski, Mateusz, Todd, John, Cotter, Gad, Metra, Marco, Jankowska, Ewa A., Banasiak, Waldemar, Ponikowski, Piotr

Journal:

European Journal of Heart Failure

Year:

2019

Language:

english

File:

PDF, 273 KB

english, 2019

10

Increased toxicity of high-dose furosemide versus low-dose dopamine in the treatment of refractory congestive heart failure

Cotter, Gad, Weissgarten, Jeoshua, Metzkor, Einat, Moshkovitz, Yaron, Litinski, Irena, Tavori, Uri, Perry, Chava, Zaidenstein, Ronit, Golik, Ahuva

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 725 KB

english, 1997

11

Permutation criteria to evaluate multiple clinical endpoints in a proof-of-concept study: lessons from Pre-RELAX-AHF

Beth A. Davison, Gad Cotter, Hengrui Sun, Li Chen, John R. Teerlink, Marco Metra, G. Michael Felker, Adriaan A. Voors, Piotr Ponikowski, Gerasimos Filippatos, Barry Greenberg, Sam L. Teichman, Elaine

Journal:

Clinical Research in Cardiology

Year:

2011

Language:

english

File:

PDF, 205 KB

english, 2011

12

Relaxin, a pleiotropic vasodilator for the treatment of heart failure

Sam L. Teichman, Elaine Unemori, Thomas Dschietzig, Kirk Conrad, Adriaan A. Voors, John R. Teerlink, G. Michael Felker, Marco Metra, Gad Cotter

Journal:

Heart Failure Reviews

Year:

2009

Language:

english

File:

PDF, 502 KB

english, 2009

13

Vasodilators in the treatment of acute heart failure: what we know, what we don’t

Marco Metra, John R. Teerlink, Adriaan A. Voors, G. Michael Felker, Olga Milo-Cotter, Beth Weatherley, Howard Dittrich, Gad Cotter

Journal:

Heart Failure Reviews

Year:

2009

Language:

english

File:

PDF, 223 KB

english, 2009

14

Relaxin: Review of Biology and Potential Role in Treating Heart Failure

Sam L. Teichman, Elaine Unemori, John R. Teerlink, Gad Cotter, Marco Metra

Journal:

Current Heart Failure Reports

Year:

2010

Language:

english

File:

PDF, 199 KB

english, 2010

15

Early worsening heart failure in patients admitted with acute heart failure – a new outcome measure associated with long-term prognosis?

Beth Davison Weatherley, Olga Milo-Cotter, G. Michael Felker, Nir Uriel, Edo Kaluski, Zvi Vered, Christopher M. O’Connor, Kirkwood F. Adams, Gad Cotter

Journal:

Fundamental & Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 110 KB

english, 2009

16

Inflammatory activation: cardiac, renal, and cardio-renal interactions in patients with the cardiorenal syndrome

Paolo C. Colombo, Anjali Ganda, Jeffrey Lin, Duygu Onat, Ante Harxhi, Julia E. Iyasere, Nir Uriel, Gad Cotter

Journal:

Heart Failure Reviews

Year:

2012

Language:

english

File:

PDF, 340 KB

english, 2012

17

Atropine-facilitated electrical cardioversion of persistent atrial fibrillation

Edo Kaluski, Alex Blatt, Marina Leitman, Ricardo Krakover, Zvi Vered, Gad Cotter

Journal:

The American Journal of Cardiology

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

18

Influence of conduction disturbances on clinical outcome in patients with acute myocardial infarction receiving thrombolysis (results from the ARGAMI-2 study)

Aiden Abidov, Edo Kaluski, Hanoch Hod, Johnatan Leor, Zvi Vered, Shmuel Gottlieb, Solomon Behar, Gad Cotter

Journal:

The American Journal of Cardiology

Year:

2004

Language:

english

File:

PDF, 96 KB

english, 2004

19

Screening for Depression and Suicidality in Patients With Cardiovascular Illnesses

Eyal Shemesh, Rachel A. Annunziato, David Rubinstein, Sarah Sultan, Jotinder Malhotra, Mugdha Santra, Beth D. Weatherley, John R. Feaganes, Gad Cotter, Rachel Yehuda

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 179 KB

english, 2009

20

Comparison of inflammatory and neurohormonal activation in cardiogenic pulmonary edema secondary to ischemic versus nonischemic causes

Olga Milo, Gad Cotter, Edo Kaluski, Alex Brill, Alex Blatt, Ricardo Krakover, Zvi Vered, Rami Hershkoviz

Journal:

The American Journal of Cardiology

Year:

2003

Language:

english

File:

PDF, 439 KB

english, 2003

21

Usefulness of losartan, captopril, and furosemide in preventing nitrate tolerance and improving control of unstable angina pectoris

Gad Cotter, Einat Metzkor-Cotter, Edo Kaluski, Alex Blatt, Irena Litinsky, Yehuda Baumohl, Yaron Moshkovitz, Zvi Vered, Ronit Zaidenstein, Ahuva Golik

Journal:

The American Journal of Cardiology

Year:

1998

Language:

english

File:

PDF, 100 KB

english, 1998

22

Minimal heparinization in coronary angioplasty—how much heparin is really warranted?

Edo Kaluski, Ricardo Krakover, Gad Cotter, Alberto Hendler, Itzhak Zyssman, Olga Milovanov, Alex Blatt, Ester Zimmerman, Edna Goldstein, Vera Nahman, Zvi Vered

Journal:

The American Journal of Cardiology

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

23

A prospective study of posttraumatic stress symptoms and nonadherence in survivors of a myocardial infarction (MI)

Eyal Shemesh, Abraham Rudnick, Edo Kaluski, Olga Milovanov, Ahmed Salah, Daniela Alon, Irit Dinur, Alex Blatt, Mikael Metzkor, Ahuva Golik, Zvi Verd, Gad Cotter

Journal:

General Hospital Psychiatry

Year:

2001

Language:

english

File:

PDF, 658 KB

english, 2001

24

Intracoronary administration of autologous bone marrow mononuclear cells after induction of short ischemia is safe and may improve hibernation and ischemia in patients with ischemic cardiomyopathy

Alex Blatt, Gad Cotter, Marina Leitman, Ricardo Krakover, Edo Kaluski, Olga Milo-Cotter, Igor B. Resnick, Simcha Samuel, David Gozal, Zvi Vered, Shimon Slavin, Michael Y. Shapira

Journal:

American Heart Journal

Year:

2005

Language:

english

File:

PDF, 118 KB

english, 2005

25

The pathophysiology of acute heart failure—Is it all about fluid accumulation?

Gad Cotter, G. Michael Felker, Kirkwood F. Adams, Olga Milo-Cotter, Christopher M. O'Connor

Journal:

American Heart Journal

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

26

Phase III clinical trial end points in acute heart failure syndromes: A virtual roundtable with the acute heart failure syndromes international working group

Mihai Gheorghiade, Kirkwood F. Adams, John G.F. Cleland, Gad Cotter, G. Michael Felker, Gerasimos S. Filippatos, Gregg C. Fonarow, Barry H. Greenberg, Adrian F. Hernandez, Sadiya Khan, Michel Komajda,

Journal:

American Heart Journal

Year:

2009

Language:

english

File:

PDF, 597 KB

english, 2009

27

The PROTECT Pilot Study: A Randomized, Placebo-Controlled, Dose-Finding Study of the Adenosine A1 Receptor Antagonist Rolofylline in Patients With Acute Heart Failure and Renal Impairment

Gad Cotter, Howard C. Dittrich, Beth Davison Weatherley, Daniel M. Bloomfield, Christopher M. O'connor, Marco Metra, Barry M. Massie

Journal:

Journal of Cardiac Failure

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

28

Early Worsening Heart Failure in Patients Admitted for Acute Heart Failure: Time Course, Hemodynamic Predictors, and Outcome

Guillermo Torre-Amione, Olga Milo-Cotter, Edo Kaluski, Loic Perchenet, Isaac Kobrin, Aline Frey, Michele M. Rund, Beth Davison Weatherley, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2009

Language:

english

File:

PDF, 147 KB

english, 2009

29

Vasodilators in Acute Heart Failure (AHF): Does Blood Pressure Matter? Results from Pre-Relax-AHF

John R. Teerlink, Marco Metra, G. Michael Felker, Adriaan A. Voors, Barry H. Greenberg, Piotr Ponikowski, Sam L. Teichman, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2009

Language:

english

File:

PDF, 110 KB

english, 2009

30

Worsening Renal Function in Acute Heart Failure: Change in Blood Pressure and Effects of Relaxin

G. Michael Felker, Adriaan A. Voors, Marco Metra, John R. Teerlink, Piotr Ponikowski, Barry H. Greenberg, Elaine Unemori, Gad Cotter, Sam L. Teichman

Journal:

Journal of Cardiac Failure

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

31

Time to Treatment and Vasodilator Efficacy in Acute Heart Failure: Results from the Pre-RELAX-AHF Study

G. Michael Felker, John R. Teerlink, Piotr Ponikowski, Adriaan A. Voors, Gerasimos Filippatos, Barry H. Greenberg, Sam L. Teichman, Gad Cotter, Beth D. Weatherley, Marco Metra

Journal:

Journal of Cardiac Failure

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

32

Troponin Release in Patients Admitted with Acute Decompensated Heart Failure and Renal Dysfunction: Results from the Pilot Phase of the PROTECT Trial

Marco Metra, Howard C. Dittrich, Gad Cotter, Barry M. Massie, Piotr Ponikowski, Gang Jia, Kenji P. Fujita, Christopher M. O'Connor

Journal:

Journal of Cardiac Failure

Year:

2009

Language:

english

File:

PDF, 555 KB

english, 2009

33

Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function

Beth Davison Weatherley, Gad Cotter, Howard C. Dittrich, Paul DeLucca, George A. Mansoor, Daniel M. Bloomfield, Piotr Ponikowski, Christopher M. O'Connor, Marco Metra, Barry M. Massie

Journal:

Journal of Cardiac Failure

Year:

2010

Language:

english

File:

PDF, 217 KB

english, 2010

34

The Effects of Adenosine A1 Receptor Antagonism in Patients With Acute Decompensated Heart Failure and Worsening Renal Function: The REACH UP Study

Stephen S. Gottlieb, Michael M. Givertz, Marco Metra, Kevin Gergich, Steven Bird, Charlotte Jones-Burton, Barry Massie, Gad Cotter, Piotr Ponikowski, Beth Weatherley, Christopher O'Connor, Howard Ditt

Journal:

Journal of Cardiac Failure

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

35

Evaluating Treatment Efficacy by Multiple Endpoints in Phase II Acute Heart Failure Clinical Trials: Analyzing Data Using a Global Method

Hengrui Sun, Beth Davison, Gad Cotter, Michael Pencina, Gary Koch

Journal:

Journal of Cardiac Failure

Year:

2012

Language:

english

File:

PDF, 89 KB

english, 2012

36

Patterns of leukocyte counts on admissions for acute heart failure — presentation and outcome — results from a community based registry

Olga Milo-Cotter, G. Michael Felker, Nir Uriel, Edo Kaluski, Christopher Edwards, Michele M. Rund, Beth Davison Weatherley, Gad Cotter

Journal:

International Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 357 KB

english, 2011

37

Nitrates for myocardial infarction

Gad Cotter, Einat Metzkor-Cotter, Edo Kaluski, Ahuva Golik

Journal:

Year:

1998

Language:

english

File:

PDF, 55 KB

english, 1998

38

High-dose nitrates in the immediate management of unstable angina: Optimal dosage, route of administration, and therapeutic goals

Gad Cotter, Hedy Faibel, Paul Barash, Eyal Shemesh, Yaron Moshkovitz, Einat Metzkor, Avi Simovitz, Rami Miller, Zwi Schlezinger, Ahuva Golik

Journal:

The American Journal of Emergency Medicine

Year:

1998

Language:

english

File:

PDF, 675 KB

english, 1998

39

Prior peripheral arterial disease and cerebrovascular disease are independent predictors of adverse outcome in patients with acute coronary syndromes: Are we doing enough? Results from the Orbofiban in Patients with Unstable Coronary Syndromes-Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study

Gad Cotter, Christopher P. Cannon, Carolyn H. McCabe, Yoav Michowitz, Edo Kaluski, Andrew Charlesworth, Olga Milo, Jane Bentley, Alex Blatt, Rikardo Krakover, Reuven Zimlichman, Leonardo Reisin, Alon

Journal:

American Heart Journal

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

40

Site Matters: Winning the Hearts and Minds of Patients in a Cardiology Clinic

Rachel A. Annunziato, David Rubinstein, Saqib Sheikh, Martin Maurer, Gad Cotter, Mary M. Mckay, Olga Milo-Cotter, Jack M. Gorman, Eyal Shemesh

Journal:

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

41

Is High Cholesterol Associate with Improved Survival in Patients with CHF Due to a More Pronounced Effect Statins Therapy in Patients with High- Cholesterol? Results from the Placebo Arm of the ENABLE Study

Olga Milo, Isaac Kobrin, Maurizio Rainisio, Tina Moriconni, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 44 KB

english, 2004

42

Intra-Coronary Administration of Un Manipulated Autologus Bone Marrow after Induction of Short Ischemia is Safe and may Improve Ischemia and Hibernation in Patients with Ischemic Cardiomyopathy

Alex Blatt, Gad Cotter, Marina Laitman, Rikardo Karakover, Zvi Vered

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 106 KB

english, 2004

43

Whole-body electrical bio-impendance is accurate in non invasive determination of cardiac output: a thermodilution controlled, prospective, double blind evaluation

Guillermo Torre-Amione, Olga Milo, Edo Kaluski, Zvi Vered, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 120 KB

english, 2004

44

Hemodynamic variables (cardiac power) and their changes during 6 hours are the strongest predictors of short-term outcome in acute heart failure

Guillermo Torre-Amione, Olga Milo, Edo Kaluski, Aline Frey, Loic Perchenet, Nir Uriel, Zvi Vered, Isaac Kobrin, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 90 KB

english, 2004

45

The daily incidence of acute heart failure is strongly correlated with cold weather conditions and air pollution. cold immersion pulmonary oedema revisited?

Olga Milo, Ilan Sewter, Edo Kaluski, Nir Uriel, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 44 KB

english, 2004

46

Non-invasive measurement of cardiac output by whole-body bio-impedance during dobutamine stress echocardiography: clinical implications in patients with left ventricular dysfunction and ischemia

Gad Cotter, Marina Laitman, Edgar Sucher, Eli Peleg, Edo Kaluski, Ruth Wolf, Zvi Vered

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 77 KB

english, 2004

47

Echocardiographic ejection fraction in patients with acute heart failure: weak correlations with cardiac contractility and short-term outcome

Nir Uriel, Guillermo Torre-Amione, Olga Milo, Edo Kaluski, Aline Frey, Loic Perchenet, Zvi Vered, Isaac Kobrin, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2004

Language:

english

File:

PDF, 53 KB

english, 2004

48

The Daily Incidence of Acute Heart Failure Is Correlated With Low Minimal Night Temperature: Cold Immersion Pulmonary Edema Revisited?

Olga Milo-Cotter, Ilan Setter, Nir Uriel, Edo Kaluski, Zvi Vered, Ahuva Golik, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

49

Rapid (2 Minutes) Clinical Assessment of Respiratory Failure (Oxygen Saturation) and Circulatory Failure (Systolic Blood Pressure) – An Easy and Acurate Way To Risk Stratify Patients with Acute Heart Failure at Admission?

Olga Milo-Cotter, Nir Uriel, Michael Felker, Beth Weatherly, Edo Kalusi, Zvi Vered, Christopher M. O'Connor, Gad Cotter

Journal:

Journal of Cardiac Failure

Year:

2006

Language:

english

File:

PDF, 54 KB

english, 2006

50

Serial Changes in Symptoms and Signs of Heart Failure in Patients Admitted for Acute Heart Failure – The Measure HF Study

Marco Metra, Gerasimos Fillipatos, Eduardo Reisin, Daniel Bensimhon, Eduardo Gronda, Gad Cotter, Eric J. Velazquez, Beth D. Weatherly, O'Connor Christopher M., Howard C. Dittrich, Michael Tansey

Journal:

Journal of Cardiac Failure

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006